The Celiac Disease panel tests for antibodies that typically develop in patients with Celiac Disease, and it’s mainly used to help diagnose and/or monitor the disease.
Celiac disease is an autoimmune disorder that is caused by an adverse immune response to gluten, which is a protein found in wheat, and related dietary proteins in rye and barley.
Our Celiac panel offers an IgA value, which can help determine if someone had a condition that may lead to an IgA antibody deficiency. It’s possible that some people with Celiac Disease may show false negatives on IgA antibody tests. If that is the case, the results of the IgG antibody tests in this panel will be more accurate in understanding the patient’s status.
This panel was developed for patients who are experiencing symptoms associated with Celiac Disease, or those that have family members who have been diagnosed with the disease. Consult with your physician for a complete understanding of the disease and what your results indicate.
Tissue Transglutaminase, IgA - primary test ordered to screen for celiac disease. It is the most sensitive and specific blood test for celiac disease
Deamidated Gliadin Peptide, IgA - looks for the level of deamidated gliadin antibodies (DMG) in your blood. Gliadin is one of the main proteins in gluten. The test is used to help find out whether you have celiac disease, an autoimmune disease
Tissue Transglutaminase, IgG - may be ordered as an alternative in those who have a deficiency of IgA. If the anti-tTG, IgA or IgG test is positive, then the test can also be used to monitor a person with celiac disease and to help evaluate the effectiveness of treatment; antibody levels should fall when gluten is removed from the diet. Although "tissue" is in the name of these tests, they are measured in the blood
Deamidated Gliadin Peptide, IgG - Detection of antibodies to gliadin, one of the major protein components of gluten, is a sensitive assay useful in diagnosing celiac disease