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COVID-19 | Q&A COVID-19 IgG & IgM Antibodies

General information:

What is an IgM and what is an IgG? Upon infection with the SARS-CoV-2 virus, the patient’s immune system tries to fight the virus by producing blood- circulating molecules known as antibodies. IgM is a class of antibodies that appears early after an infection (as early as 3-5 days).

IgM is the body’s first line of defense against a foreign antigen. IgG is another class of antibodies that appears later and gradually replaces the IgM antibodies.

Usually, IgG antibodies appear in the blood circulation within 3-4 weeks after initial infection. The presence of SARS-CoV-2-specific IgM and/or IgG antibodies in the blood of a patient is a strong indication that the patient has been infected with the SARS-CoV-2 virus.

1.How long does it take to develop the IgG & IgM antibodies after exposure to the Coronavirus?

A.IgM as early as 3-5 days. IgG as early as 3-4 weeks post infection.

2.What does a positive IgG result mean?

A. Most likely the individual was exposed at least 3 - 4 weeks prior to testing.

3.What does a positive IgM result mean?

A. IgM is the body’s first line of defense against a foreign antigen, so the individual was recently exposed to an infection (as early as 3-5 days)

4.If neither are positive, does this mean the patient was never exposed?

A. No, only the Real Time RT-PCR,DNA, swab test is a current indicator searching for the presence of SARS-CoV-2.

5.If a patient shows the presence of the antibodies, does this mean they cannot become infected with the virus in the future?

A. If the IgG is positive, there is a good chance the individual’s body built a defense against the virus.

6.How long will it take to receive results?

A. Within 24hrs

7.Is this an at home test?

A. No, this requires a venipuncture by a healthcare professional and will be tested in our CLIA certified High Complexity Lab

8.Who can order this test?

A.Physicians or Patients that will have their blood drawn by a healthcare professional.

9.How do I order COVID-19 IgG & IgM antibody testing?

A.Log into your online account, create a new requisition on your patient and use order code #C19P. Ship the blood to us using our transport boxes.

10. Can I send my patients to a draw site to be collected for this test?


11.Can a mobile phlebotomist be sent to my patients for this test?


12.What are the accepted specimen requirements, stability, shipping protocols?

A.Serum in an SST tube. Spin tube after 15min of draw. Ship ambient and it is stable for 48hrs.

13.What is the test methodology for COVID-19 IgG & IgM Antibody Testing?

A.Chemiluminescense ImmunoAssay

14.How is your test different from other rapid at-home antibody tests?

A.This is not an “at home test”. This test is performed at a CLIA certified lab that is CAP accredited.

15.What is the clinical specificity of this test?


16.What is the clinical sensitivity of this test?


17.Does the Testing and Instrumentation follow FDA guidelines?

A.Yes, all testing and instrumentation follows FDA guidance.

18.Does Access accept insurance for this testing?